When green algae "can’t breathe",
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Haemoglobin an old protein in a new look
In the human body,
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70% Off 2014 Teal Grey & White Chevron Roshe Runs, says Prof. Thomas Happe from the Work Group Photobiotechnology. Nature has produced a large number of related proteins which fulfil different functions. The green alga Chlamydomonas reinhardtii has what is known as a "truncated" haemoglobin,
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In an oxygen free environment, the green alga activates specific genes
When Chlamydomonas has no oxygen available,
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A haemoglobin and nitric oxide help green algae to survive
The scientists studied the haemoglobin protein and its genetic blueprint in more detail using molecular biological and biochemical analyses. "One thing became clear very quickly",
Buy Cheap Online Nike Rose, says Dr. Anja Hemschemeier from the Work Group Photobiotechnology. "Algae in which we switched this gene off could hardly grow without oxygen." From previous studies it is known that in many organisms, haemoglobin detoxifies nitric oxide,
Discount Free Hot Pink, because an overdose of this gas poisons the cells. The biologists therefore tested whether green algae which are no longer able to form haemoglobin after genetic manipulation die of nitric oxide poisoning. Their expectations: the green algae should fare better if the gas is removed using a chemical scavenger. "Surprisingly,
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Nitric oxide signals: "no oxygen!"
Nitric oxide acts in many living organisms as a signalling molecule apparently also in green algae. Experiments in vitro have shown that the green algal haemoglobin interacts with nitric oxide. When the researchers artificially introduced the gas to the single cell organisms,
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Store Online Womens Shoes Tiffany Blue Nikes, Happe sums up. His team wants to go on exploring the role of this protein in green algae, as the biologists have discovered another eleven haemoglobin genes in the organism. "Now things are really getting going", says the Bochum scientist. "The map of haemoglobin research has many blank spots that we want to fill with content. The fact that a single cell requires twelve haemoglobin proteins indicates that these fulfil finely tuned functions in the cell."
A. Hemschemeier,
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Wholesale Nike Free Tiffany Blue, D. Merchant, M. Winkler, T. Happe (2013): Hypoxic survival requires a 2 on 2 hemoglobin in a process involving nitric oxide, Proceedings of the National Academy of Sciences, doi: 10.1073/pnas.1302592110.
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